A new survival reality show, The Game of Queen Bee, invites you to the world of queen bees and their males where they compete for the prize money of 100,000 dollars in wild environments. The six queen bees, Monika, Jang Eun Sil, Jeong He Jin, Seo Hyun Suk, Shin Ji Eun, and Gooseul, must each lead three male participants in extreme survival missions and physical fights amid suffocating psychological warfare. The queen bees must lead their team members wisely and efficiently using the strategies and tactics they come up with as a team in order to win.