As winter drags on Charles, Dr. Pol and the rest of clinic staff brave the frigid temperatures to keep animals healthy in the clinic and on the farm. The first stop is an organic farm where the owner recently lost two calves to a mysterious infection. Across town, Dr. Brenda is called out to visit a 10-month-old horse who has cut his leg badly on a rusty trailer. Later, Dr. Pol and Charles investigate two bizarre cases, both involving birth defects at the opposite ends of two young calves!