Season 5 picks up with James “Ghost” St. Patrick in a dangerous alliance with his former drug partner Tommy Egan and mortal enemy Kanan Stark. As Ghost mourns, he searches for vengeance and throws himself into his work, reaching new, professional heights. But with this newfound publicity, his quest for blood threatens to dismantle his legitimate legacy. Ghost is blind to new enemies and, as the Feds grow closer to unmasking his true identity, Ghost must remain vigilant toward those wanting to take him down for his past criminal enterprises.