Pandora seals away Alone in his studio so that he can focus on the creation of the Lost Canvas, and completely awaken as Hades. In the shadows, Hades's councillors Hypnos and Thanatos, worried about the Pegasus Saint and his connections to Hades, begin to take action. At the Pope's orders, the Cancer Saint Manigoldo follows after Tenma. On his way to Hades's Cathedral, Tenma reaches the spot where his old village was destroyed, but in its place he finds a gigantic and sinister forest.