When Mr. Whiskers falls out of the tree for yet another time, Brandy insults him, saying that he never uses his brain. However, Mr. Whiskers' brain agrees with her, so he decides to leave his brain and head off to live his own life. Mr. Whiskers begins to become depressed as he feels lonely without his brain inside of his head, so Brandy decides to head off to find Mr. Whiskers' brain in order to return it to the rightful place where it belongs, though how will she manage to convince his brain to go back to the place he hates?