The Biker Mice have big problems: Stoker has been kidnapped by Rump and the Catatonians who have used the Regenerator to turn Limburger and Brie into fish while Carbunkle collaborates with Dr. Catorkian. Rump himself wants to conquer Earth by replacing world leaders with Greasepit and the aliens that Limburger apprehended while Dr. Carbunkle and Dr. Catorkian work to modify the Regenerator. Can the Biker Mice save Stoker and the Earth before it's too late?